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Article

Classification of mutations at the HLA-A locus by use of the polymerase chain reaction.

Environmental and molecular mutagenesis - 1 Jan 1993

Joseph G, Grist S, Firgaira F, Turner D, Morley A

Abstract excerpt

We investigated whether the polymerase chain reaction (PCR) could be used to determine the mechanism of mutation in lymphocyte clones mutated at the HLA-A locus. Three polymorphisms, at Factor XIIIA, D6S109, and intron 3 of the HLA-A gene, were used to study a series of clones previously characterised by Southern blotting (SB) at multiple loci on chromosome 6. For detection of loss of heterozygosity, the results...

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Identifiers

PMID: 8104787
DOI: 10.1002/em.2850220307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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