Multiple phenotypic divergence of mammary adenocarcinoma cell clones. II. Sensitivity to radiation, hyperthermia and FUdR.

doi:10.1007/BF00135173

Back to search

Article

Multiple phenotypic divergence of mammary adenocarcinoma cell clones. II. Sensitivity to radiation, hyperthermia and FUdR.

Clinical & experimental metastasis - 1 Jan 2000

Welch D R, Evans D P, Tomasovic S P, Milas L, Nicolson G L

Abstract excerpt

We have shown that, with in vitro passage, subclones derived from clonal cell populations of 13762NF mammary adenocarcinoma undergo phenotypic drift and diversification in their cellular properties. Here we examine whether phenotypic divergence of 13762NF cell clones extends to therapeutic treatments used in eliminating mammary tumors and whether the apparent rates of phenotypic divergence vary for different...

Topics

Adenocarcinoma
Animals
Cell Survival
Cells, Cultured
Clone Cells
Dose-Response Relationship, Radiation
Female
Floxuridine
Gamma Rays
Hot Temperature
Mammary Neoplasms, Experimental

Phenotype

Rats

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest

Multiple phenotypic divergence of mammary adenocarcinoma cell clones. II. Sensitivity to radiation, hyperthermia and FUdR.PMID 6242285Read

Multiple phenotypic divergence of mammary adenocarcinoma cell clones. I. In vitro and in vivo properties.Semantic proximity Read

Human thyroid cancer cells as a source of iso-genic, iso-phenotypic cell lines with or without functional p53.Semantic proximity Read

Changes of phenotypic characteristics of variants derived from Lewis lung carcinoma during long-term in vitro growth.Semantic proximity Read

A hitchhiker’s guide to cancer modelsSemantic proximity Read

Chemotherapy reshapes cellular clonal landscape via persister programs in breast cancer xenograftsSemantic proximity Read

Genetic and transcriptional evolution alters cancer cell line drug response.Semantic proximity Read

Sequentially-induced responses define tumour cell radiosensitivity.Semantic proximity Read

The role of clonal communication and heterogeneity in breast cancerSemantic proximity Read