Article
Immunogenetic differences between patients with familial and non-familial rheumatoid arthritis.
Annals of the rheumatic diseases - 1 Mar 2000
Laivoranta-Nyman S, Möttönen T, Luukkainen R, Hakala M, Yli-Kerttula U, Hannonen P, Tuokko J, Toivanen A, Ilonen J
Abstract excerpt
OBJECTIVE: To search for possible immunogenetic differencies between the patients with familial and non-familial rheumatoid arthritis (RA). METHODS: The study compared 129 familial RA patients with 217 non-familial patients for the frequencies of HLA-DR antigens including DR4 subtypes, DR4-DQB1*0301 and DR4-DQB1*0302 haplotypes and HLA-B27 antigen as well as the age of disease onset and existence of rheumatoid...
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