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Article

HLA-DRB1 genes in 5 rheumatic disease multi-case families.

Chinese medical journal - 1 Mar 1998

Tian X, Jiang M, Qiu C

Abstract excerpt

OBJECTIVE: To detect HLA-DRB1 (DR1-10) alleles in 5 families with multi-case rheumatic diseases, and to study the possible influence of DRB1 genes in the pathogenesis of rheumatic diseases. METHODS: Sequence-Specific Primer PCR (PCR-SSP) method was used to examine HLA-DRB1 alleles. Totally 36 members of 5 families and 166 healthy people were involved in this study. The results were assessed by Chi-square test....

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PMID: 10374416

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