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Article

Three-dimensional structure of an antigenic mutant of the influenza virus haemagglutinin.

Nature - 1 Jan 2000

Knossow M, Daniels R S, Douglas A R, Skehel J J, Wiley D C

Abstract excerpt

Antigenic variation in the haemagglutinin (HA) glycoprotein of influenza virus is associated with recurrent epidemics of respiratory disease in man (for review see ref. 1). We have examined the size of structural changes necessary to alter the antigenicity of HA by determining the three-dimensional structure of the HA from an antigenic mutant containing a single amino acid substitution which was selected by...

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PMID: 6207440
DOI: 10.1038/311678a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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