Article
Recombinogenic and mutagenic effects of the antitumor antibiotic bleomycin in Aspergillus nidulans.
Mutation research - 1 Jan 2000
Demopoulos N A, Kappas A, Pelecanos M
Abstract excerpt
Bleomycin, an antibiotic and antineoplastic drug that inhibits DNA synthesis and causes several types of chromosomal aberration, was found to increase mitotic recombination in Aspergillus nidulans. Heterozygous prototrophic diploid strains grown on media containing bleomycin produced significant increases of yellow and white sectors compared with controls. Further, the increased colour segregants were due to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
