Systems and results of tests for chemical induction of mitotic malsegregation and aneuploidy in Aspergillus nidulans.

Abstract excerpt

In Aspergillus several types of test systems have been developed for detection of chemicals which induce aneuploidy and/or malsegregation of chromosomes. Results from 23 papers were reviewed in which numerical data for 42 chemicals had been reported. The test systems fall into two groups. One group includes all purely genetic tests that detect euploid mitotic segregants from heterozygous diploids and identify...

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