Article
Parameiosis in Aspergillus nidulans in response to doxorubicin.
Folia microbiologica - 1 Jan 2004
Becker T C A, De Castro-Prado M A A
Abstract excerpt
The recombinagenic effect of doxorubicin (an anticancer agent that impairs DNA synthesis and causes chromosome breaks) was used to induce parameiotic events in Aspergillus nidulans. Heterokaryons formed with master strains and uvs mutants were inoculated with and without doxorubicin. Haploid segregants (parameiotics and parents) and aneuploids were selected as heterokaryon-derived visible sectors. Among...
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