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Article

Vincristine induces somatic segregation, via mitotic crossing-over, in diploid cells of Aspergillus nidulans.

Biological research - 1 Jan 2002

Chiuchetta Simone Jurema Ruggeri, De Castro-Prado Marialba Avezum Alves

Abstract excerpt

Vincristine is an alkaloid widely used as an antineoplastic agent. In eukaryotic cells the drug causes blockage in the G2 phase of the cell cycle and an increase in the frequency of sister chromatid exchanges. Due to the fact that germinating Aspergillus nidulans cells spend most of their cycle in G2 phase, they provide an excellent system for the study of mitotic crossing-over. Taking into account that mitotic...

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Source

Identifiers

PMID: 12125202
DOI: 10.4067/s0716-97602002000100006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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