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Article

Social Determinants and Brain Health in PSEN1 E280A Carriers vs Non-Carriers: A Colombian Cohort.

American journal of Alzheimer's disease and other dementias - 1 Jan 2026

Tumbajoy-Arango C Vanessa, Trujillo Natalia, Sánchez Juan Pablo, Díaz Diego Camilo, Valencia Stella, Trujillo Sandra, Gómez Diana

Abstract excerpt

Social determinants of health (SDOH), including education, socioeconomic status, place of residence, genetic risk, and perceived stress, influence brain health and Alzheimer's disease (AD), yet their role in genetically at-risk populations remains underexplored. This study examined the influence of SDOH on early brain health, specifically its cognitive dimension, in Colombian individuals from the world's largest...

Read the complete abstract on PubMed

Topics

Humans
Colombia
Female
Male
Alzheimer Disease
Presenilin-1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Middle Aged

Social Determinants of Health

Brain

Cohort Studies

Heterozygote

Aged

Subjective Stress

Adult

Educational Status

Mutation

Source

Identifiers

PMID: 42771764
DOI: 10.1177/15333175261492405

Genes

PSEN1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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