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Health-Related Behaviors and Risk of Common Age-Related Brain Diseases Across Severities of Genetic Risk.

Neurology - 26 Nov 2024

Marini Sandro, Kimball Tamara N, Mayerhofer Ernst, Tack Reinier W P, Senff Jasper R, Prapiadou Savvina, Rivier Cyprien A, Duskin Jonathan, Kourkoulis Christina, Falcone Guido J, Yechoor Nirupama, Tanzi Rudolph E, Rosand Jonathan, Singh Sanjula, Parodi Livia, Anderson Christopher D

Abstract excerpt

BACKGROUND AND OBJECTIVES: The 21-point Brain Care Score (BCS) is an index that ranks behaviors and clinical measurements with the aim of encouraging lifestyle adjustments to lower the incidence of age-related brain disease, including stroke, late-life depression (LLD), and dementia. A higher BCS at baseline is associated with a lower risk of these outcomes. We aimed to investigate whether the associations...

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PMID: 39504504
DOI: 10.1212/WNL.0000000000210014

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