Genetic variation in the TSLP promoter is associated with Hashimoto's thyroiditis comorbidity in patients with chronic spontaneous urticaria.

doi:10.15586/aei.v54i5.1606

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Article

Genetic variation in the TSLP promoter is associated with Hashimoto's thyroiditis comorbidity in patients with chronic spontaneous urticaria.

Allergologia et immunopathologia - 1 Jan 2026

Egea-Bermejo Eduardo, Fang Luis, Arroyo-Movilla Carlos Octavio, Domínguez-Vargas Alex, Moreno-Woo Ana, De Egea Gloria Garavito

Abstract excerpt

BACKGROUND: Chronic spontaneous urticaria (CSU) is a systemic immune-mediated disorder frequently comorbid with autoimmune thyroid disease, particularly Hashimoto's thyroiditis (HT). Emerging evidence implicates shared immunogenetic pathways, yet the role of thymic stromal lymphopoietin (TSLP), a key epithelial alarmin in this comorbidity remains unclear. OBJECTIVE: To investigate the association between TSLP...

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Topics

Humans
Thymic Stromal Lymphopoietin
Cytokines
Female
Male
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Adult

Chronic Urticaria

Hashimoto Disease

Promoter Regions, Genetic

Middle Aged

Genetic Predisposition to Disease

Comorbidity

Genotype

Source

Open in PubMed

Identifiers

PMID: 42760875
DOI: 10.15586/aei.v54i5.1606

Genes

TSLP
TPO

Provenance

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