[Clinical characteristics and prognosis of acute myeloid leukemia patients with RUNX1 single-site and multiple-site gene mutations].

doi:10.3760/cma.j.cn121090-20251020-00473

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

[Clinical characteristics and prognosis of acute myeloid leukemia patients with RUNX1 single-site and multiple-site gene mutations].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 14 Jun 2026

Li C, Wu Y X, Ma X, Chen S N, Wu D P, Hu X H

Abstract excerpt

Objective: To compare the clinical characteristics and prognosis of patients with acute myeloid leukemia (AML) harboring single-site versus multi-site mutations in the RUNX1 gene. Methods: This study was a retrospective cohort study. 145 patients with RUNX1-mutated AML treated at the First Affiliated Hospital of Soochow University between June 2017 and June 2023 were selected. Single-site RUNX1 mutations were...

Read the complete abstract on PubMed

Topics

Humans
Core Binding Factor Alpha 2 Subunit
Leukemia, Myeloid, Acute
Female
Male
Prognosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Mutation

Adult

Middle Aged

Retrospective Studies

Adolescent

Aged

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 42706154
DOI: 10.3760/cma.j.cn121090-20251020-00473
PMCID: PMC13575522

Genes

RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Clinical characteristics and prognosis of acute myeloid leukemia patients with RUNX1 single-site and multiple-site gene mutations].PMID 42706154Read ↗

[Clinical characteristics of RUNX1-mutated acute myeloid leukemia patients].Semantic proximity Read ↗

Investigations of the prognostic value of RUNX1 mutation in acute myeloid leukemia patients: Data from a real-world study.Semantic proximity Read ↗

Impact of RUNX1 mutations at distinct sites on the clinical characteristics and prognosis of patients with acute myeloid leukemia.Semantic proximity Read ↗

Genetic Mutations in Patients with Acute Myeloid Leukemia and Their Impact on Prognosis.Semantic proximity Read ↗

Frequency and impact of somatic co-occurring mutations on post-transplant outcomes in acute myeloid leukemia: a multicenter registry analysis on behalf of the EBMT ALWP.Semantic proximity Read ↗

RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features.Semantic proximity Read ↗

Immunophenotypic, Genetic, and Clinical Features Associated With RUNX1 Mutation in Acute Leukemias and Chronic Myeloid Neoplasms.Semantic proximity Read ↗

Mutational landscape of patients with acute myeloid leukemia or myelodysplastic syndromes in the context of RUNX1 mutation.Semantic proximity Read ↗

Frequency and Impact of Somatic Co-occurring Mutations on Post-Transplant Outcomes in Acute Myeloid Leukemia: A Multicenter Registry Analysis on Behalf of the EBMT ALWPSemantic proximity Read ↗

[Clinical Characteristics and Prognosis of Acute Myeloid Leukemia Patients with GATA2 Gene Mutation].Semantic proximity Read ↗

[Clinical Characteristics of Acute Myeloid Leukemia Patients with RUNX1 Gene Mutation].Semantic proximity Read ↗

[The prognostic value of cloned genetic mutations detected by second-generation sequencing in RUNX1-RUNX1T1 positive acute myeloid leukemia patients receiving intensive consolidation therapy].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.