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Article

Integration of multi-omics transcriptome-wide analysis for the identification of novel therapeutic drug targets in diabetic retinopathy.

Journal of translational medicine - 24 Dec 2024

Yi Guoguo, Li Zhengran, Sun Yuxin, Ma Xinyu, Wang Zijin, Chen Jinken, Cai Dong, Zhang Ziran, Chen Zejun, Wu Fanye, Cao Mingzhe, Fu Min

Abstract excerpt

BACKGROUND: Diabetic retinopathy (DR) is the most important complication of Type 2 Diabetes (T2D) in eyes. Despite its prevalence, the early detection and management of DR continue to pose considerable challenges. Our research aims to elucidate potent drug targets that could facilitate the identification of DR and propel advancements in its therapeutic strategies. METHODS: A broad multi-omics exploration of DR...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39719581
DOI: 10.1186/s12967-024-05856-7
PMCID: PMC11667901

Genes

SRPK1
RPS26
WFS1
DCLRE1B
ERBB3

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