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Article

Tumor Mutational Landscape and Its Correlation With Histopathological Characteristics in Breast Cancer.

Cancer genomics & proteomics - 1 Jan 2026

Papadopoulou Eirini, Stathoulopoulou Maroulio, Matiatou Maria, Karathanasis Panagiotis, Xenakis Xenofon, Pesmatzoglou Grigorios, Fyssas Ioannis, Louis Konstantinos, Maniatis Dimitrios, Ekmektzoglou Anastasia, Alexandrou Dimitrios, Kalivopoulos Christos, Kanistras Christos, Katsiakis Nikolaos, Konstantiadou Ioanna, Kavazis Christos, Kokolakis Athanasios, Papaioannou Nikolaos, Sachoulidou Anna, Sfakianakis Eleftherios, Triantafyllidou Sofia, Filippidou Sofia, Damaskos Christos, Lazaridis George, Koinis Filippos, Biziota Eirini, Koutras Angelos, Kotsori Aikaterini, Venizelos Vassileios

Abstract excerpt

BACKGROUND/AIM: In breast cancer, knowledge of the associations between clinicopathologic characteristics, genetic changes, and subtype-specific patterns is expanding. This study investigated how pathological and clinical variables affect the actionability of Next Generation Sequencing (NGS)-based tumor molecular data. MATERIALS AND METHODS: 227 breast cancer patients referred to Genekor's laboratory for tumor...

Read the complete abstract on PubMed

Topics

Humans
Female
Breast Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Mutation

Biomarkers, Tumor

High-Throughput Nucleotide Sequencing

Middle Aged

Aged

Adult

Erb-b2 Receptor Tyrosine Kinases

Microsatellite Instability

Source

Open in PubMed Open full text

Identifiers

PMID: 42674815
DOI: 10.21873/cgp.20616
PMCID: PMC13531161

Genes

TP53
ESR1
PIK3CA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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