Article
Comprehensive genomic sequencing and the molecular profiles of clinically advanced breast cancer.
Pathology - 1 Feb 2017
Ross Jeffrey S, Gay Laurie M
Abstract excerpt
Targeting specific mutations that have arisen within a tumour is a promising means of increasing the efficacy of treatments, and breast cancer is no exception to this new paradigm of personalised medicine. Traditional DNA sequencing methods used to characterise clinical cancer specimens and impact treatment decisions are highly sensitive, but are often limited in their scope to known mutational hot spots....
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