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Article

Wnt signaling as potential therapeutic target in lung cancer

16 Feb 2016

Abstract excerpt

INTRODUCTION: Wingless-type (Wnt) signaling is tightly regulated at multiple cellular levels and is dysregulated in lung cancer. Therefore, it offers therapeutic targets for developing novel agents for lung cancer treatment. AREAS COVERED: In this article, we discuss the role of the Wnt signaling pathway in lung cancer, highlighting the aberrant activation of Wnt in lung cancer stem cells and its implication in...

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PMID: 26882052
DOI: 10.1517/14728222.2016.1154945

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