Article
An Overview of miRNAs Involved in PASMC Phenotypic Switching in Pulmonary Hypertension.
BioMed research international - 1 Jan 2021
Zhang Weifang, Tao Zeying, Xu Fei, Diao Qian, Li Juan, Zhou Lu, Miao Yaxin, Xie Shanshan, Wan Jinjin, Xu Ruilai
Abstract excerpt
Pulmonary hypertension (PH) is occult, with no distinctive clinical manifestations and a poor prognosis. Pulmonary vascular remodelling is an important pathological feature in which pulmonary artery smooth muscle cells (PASMCs) phenotypic switching plays a crucial role. MicroRNAs (miRNAs) are a class of evolutionarily highly conserved single-stranded small noncoding RNAs. An increasing number of studies have...
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