Article
CircSMAD3 represses VSMC phenotype switching and neointima formation via promoting hnRNPA1 ubiquitination degradation.
Cell proliferation - 1 Jan 2025
Mei Shuai, Ma Xiaozhu, Zhou Li, Wuyun Qidamugai, Cai Ziyang, Yan Jiangtao, Ding Hu
Abstract excerpt
Circular RNAs (circRNAs) are novel regulatory RNAs with high evolutionary conservation and stability, which makes them effective therapeutic agents for various vascular diseases. The SMAD family is a downstream mediator of the canonical transforming growth factor beta (TGF-β) signalling pathway and has been considered as a critical regulator in vascular injury. However, the role of circRNAs derived from the SMAD...
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