HLAnte: A Python command-line interface for unified HLA genotype annotation with integrated pharmacogenomic, disease, and population evidence.

doi:10.1016/j.humimm.2026.112059

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Article

HLAnte: A Python command-line interface for unified HLA genotype annotation with integrated pharmacogenomic, disease, and population evidence.

Human immunology - 1 Oct 2026

Dallı Efe, Türker Duman M

Abstract excerpt

The human leukocyte antigen (HLA) system is the most polymorphic gene complex in the human genome and plays a central role in susceptibility to autoimmune disease and drug hypersensitivity. HLA typing tools arcasHLA, T1K, HLA-HD and OptiType each emit a distinct output, creating a manual reformatting bottleneck. We present HLAnte, a Python command-line interface that parses all four formats, normalizes calls...

Read the complete abstract on PubMed

Topics

Humans
HLA Antigens
Pharmacogenetics
Genotype
Software
Databases, Genetic
Gene Frequency

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Alleles

Genome-Wide Association Study

User-Computer Interface

Autoimmune Diseases

Molecular Sequence Annotation

Drug Hypersensitivity

Genome, Human

Source

Open in PubMed

Identifiers

PMID: 42641421
DOI: 10.1016/j.humimm.2026.112059

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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