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Article

Integrative Multi-omics Analysis for Prioritization of Candidate Genes in Polycystic Ovary Syndrome.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 31 Aug 2026

Guo Ruiqi, Liao Dequan, Huang Jixian, Dong Bing

Abstract excerpt

The genetic architecture of polycystic ovary syndrome (PCOS) has not been fully elucidated. Translating genome-wide association study (GWAS) loci into functional effector genes represents a key challenge for elucidating disease mechanisms and advancing targeted therapeutic strategies. In this study, the FinnGen R12 dataset was utilized in conjunction with the Genotype-Tissue Expression Project (GTEx) v8 eQTL...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42600058
DOI: 10.1096/fj.202601567R
PMCID: PMC13475956

Genes

MCM6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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