Article
Molecular genetics of polycystic ovary syndrome: an update.
Current molecular medicine - 1 Jan 2015
Li L, Baek K-H
Abstract excerpt
Polycystic ovary syndrome (PCOS) is a complex genetic disorder caused by interplay between several 'susceptibility' genes and environment factors. In the past few years, numerous studies of genomics and transcriptomics attempted to discover genes affecting PCOS. Pre-genome wide association study (GWAS) plays a stepping stone effect on the progress of PCOS, even though most of the strongest associations are for...
Topics
- Female
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
- Infertility, Female
- Inflammation
- Insulin
- Insulin Resistance
- Obesity
- Polycystic Ovary Syndrome
- Polymorphism, Single Nucleotide
- Signal Transduction
