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Article

From proteome to pathogenesis: investigating polycystic ovary syndrome with Mendelian randomization analysis.

Frontiers in endocrinology - 1 Jan 2024

Zhang Jiaqi, Li Yuqing, Gong Aixia, Wang Jingmin

Abstract excerpt

Background: Polycystic ovary syndrome (PCOS) is defined by oligo/anovulation, hyperandrogenism, and polycystic ovaries with uncertain pathogenesis. The proteome represents a substantial source of therapeutic targets, and their coding genes may elucidate the mechanisms underlying PCOS. However, reports on the profiles of the human plasma protein-coding genes and PCOS are limited. Here, we aimed to investigate...

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Identifiers

PMID: 39314522
DOI: 10.3389/fendo.2024.1442483
PMCID: PMC11417002

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