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Colocalization analysis of polycystic ovary syndrome to identify potential disease-mediating genes and proteins

4 Mar 2021

Abstract excerpt

Polycystic ovary syndrome (PCOS) is a common complex disease in women with a strong genetic component and downstream consequences for reproductive, metabolic and psychological health. There are currently 19 known PCOS risk loci, primarily identified in women of Han Chinese or European ancestry, and 14 of these risk loci were identified or replicated in a genome-wide association study of PCOS performed in up to...

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PMID: 33664499
DOI: 10.1038/s41431-021-00835-8

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