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Article

rs2357322 and rs17726078 Contribute to Breast Cancer Risk by Regulating DLX2 Expression.

The breast journal - 1 Jan 2026

Zhang Xin-Xin, Guo Hao, Li Hai-Yan, Zhou Xi-Ting, Song Hong-Li, Xu Jiang-Wei, Fu Yu-Hang, Tian Ru-Hui, Jiang Ru, Liu Chun-Chun, Sun Chang

Abstract excerpt

BACKGROUND AND AIMS: Breast cancer is the most abundant cancer type in female. Genome-wide association study suggests that rs2016394, one SNP at the intron of DLX2 divergent transcript (DLX2-DT), is significantly associated with this disease. Through 1000 genomes project data analysis, it is observed that another three SNPs, rs743605, rs2357322, and rs17726078, show strong linkage disequilibrium with rs2016394....

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Share to Breast Neoplasms
Share to Cell Line, Tumor
Share to Cell Movement
Share to Cell Proliferation
Share to Gene Expression Regulation, Neoplastic
Share to Homeodomain Proteins
Share to Linkage Disequilibrium
Share to Proto-Oncogene Mas

Source

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Identifiers

PMID: 42596720
DOI: 10.1155/tbj/3096873
PMCID: PMC13473913

Genes

DLX2
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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