Article
Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility.
Journal of human genetics - 1 Jun 2011
Kumar Vinod, Matsuo Keitaro, Takahashi Atsushi, Hosono Naoya, Tsunoda Tatsuhiko, Kamatani Naoyuki, Kong Sun-Young, Nakagawa Hidewaki, Cui Ri, Tanikawa Chizu, Seto Masao, Morishima Yasuo, Kubo Michiaki, Nakamura Yusuke, Matsuda Koichi
Abstract excerpt
Diffuse large B-cell lymphoma (DLBCL) is one of the most aggressive cancers of B-lymphocytes. To investigate genetic susceptibility factors for DLBCL, we performed single-nucleotide polymorphism based genome-wide association study (GWAS) in a total of 399 DLBCL cases and 4243 controls of Japanese population. By following two-stage GWAS approach and an independent replication study, we identified disease...
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