rs6426881 in the 3'-UTR of PBX1 is involved in breast and gastric cancers via altering the binding potential of miR-522-3p.

doi:10.1007/s11033-021-06756-5

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rs6426881 in the 3'-UTR of PBX1 is involved in breast and gastric cancers via altering the binding potential of miR-522-3p.

Molecular biology reports - 1 Nov 2021

Mohammadi Maryam, Salehzadeh Ali, Talesh Sasani Soheila, Tarang Alireza

Abstract excerpt

BACKGROUND: Breast and gastric cancers are the most important diseases that lead to cancer death and social healthcare challenge. Overexpression of PBX1, a proto-oncogene, is correlated with the progression and metastasis of various cancers. For the first time, in this study the researchers evaluated the relationship between rs6426881, affecting miR-522-3p binding to the PBX1, with breast and gastric cancers....

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PMID: 34655407
DOI: 10.1007/s11033-021-06756-5

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