Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ethnicity-specific polygenic risk score for predicting coronary heart disease mortality in Malaysian patients with type 2 diabetes.

The Medical journal of Malaysia - 1 Jul 2026

Zarkasi K A, Abdul Murad N A, Abdullah N, Mhd Yusuf N A, Abd Jalal N, Ismail N, Kamaruddin M A, Ahmad N, Jamal R

Abstract excerpt

INTRODUCTION: Polygenic risk scores (PRS) are used to aggregate single-nucleotide polymorphisms (SNPs) effects across the genome to estimate an individual's risk of coronary heart disease (CHD). However, most PRS models were developed mainly in Caucasian populations, limiting their applicability to Malaysia's diverse populations. This study aimed to develop a PRS to predict CHD mortality among individuals with...

Topics

Join the communities discussing this publication.

Aged
Coronary Disease
Diabetes Mellitus, Type 2
Ethnicity
Genetic Risk Score

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genome-Wide Association Study

Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 42584446

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ethnicity-specific polygenic risk score for predicting coronary heart disease mortality in Malaysian patients with type 2 diabetes.PMID 42584446Read ↗

Combining stacked polygenic scores with clinical risk factors improves cardiovascular risk prediction in people with type 2 diabetesSemantic proximity Read ↗

Assessing the prediction of type 2 diabetes risk using polygenic and clinical risk scores in South Asian study populationsSemantic proximity Read ↗

Genome-wide polygenic risk score for type 2 diabetes in Indian population.Semantic proximity Read ↗

Polygenic risk for coronary heart disease acts through atherosclerosis in type 2 diabetes.Semantic proximity Read ↗

Polygenic risk score refines cardiovascular disease risk in individuals with type 2 diabetes at borderline or intermediate risk.Semantic proximity Read ↗

Improved Type 2 Diabetes Risk Stratification in the Qatar Biobank Cohort by Ensemble Learning Classifier Incorporating Multi-Trait, Population-Specific, Polygenic Risk ScoresSemantic proximity Read ↗

Genetic Determinants of Coronary Artery Disease in Type 2 Diabetes Mellitus Among Asian Populations: A Meta-Analysis.Semantic proximity Read ↗

[Polygenic risk score combined with traditional risk factors for assessing the risk of type 2 diabetes mellitus among Chinese adults].Semantic proximity Read ↗

Polygenic risk, lifestyle, and cardiovascular mortality: a prospective population-based UK Biobank studySemantic proximity Read ↗

Integrated clinical risk prediction of type 2 diabetes with a multifactorial polygenic risk scoreSemantic proximity Read ↗

Comparison of polygenic risk scores for type 2 diabetes developed from different ancestry groupsSemantic proximity Read ↗

A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.