Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Causal relationship between aging-related biomarkers and osteoporosis: A bidirectional two-sample Mendelian randomization study.

The Journal of international medical research - 1 Jul 2026

Xu Rui, Sun Yin, Xu Gui-Guo, Li Hai-Bo, Zhong Hui, Peng Zhi, Lu Sheng

Abstract excerpt

ObjectiveThe potential causal role of molecular biomarkers of biological aging in osteoporosis remains uncertain. This study aimed to evaluate whether genetically predicted levels of aging-related traits are causally associated with the risk of osteoporosis.MethodsIn this study, we selected eight exposures: telomere length, mitochondrial DNA copy number, insulin-like growth factor 1 levels, DNA methylation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Biomarkers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to DNA, Mitochondrial

Share to Insulin-Like Growth Factor I

Share to Intercellular Signaling Peptides and Proteins

Share to Mendelian Randomization Analysis

Share to Osteoporosis

Source

Open in PubMed Open full text

Identifiers

PMID: 42530965
DOI: 10.1177/03000605261469014
PMCID: PMC13424525

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Causal relationship between aging-related biomarkers and osteoporosis: A bidirectional two-sample Mendelian randomization study.PMID 42530965Read ↗

Causal associations between insulin-like growth factor binding protein-1 to -7 and osteoporosis: A two-sample Mendelian randomization study.Semantic proximity Read ↗

Unveiling the Etiology of Osteoporosis Onset: A Mendelian Randomization InvestigationSemantic proximity Read ↗

Unveiling the Causal Relationship Between Osteoporosis and Circulating Metabolites from a Genetic Perspective.Semantic proximity Read ↗

Modifiable pathways for longevity: A Mendelian randomization analysis.Semantic proximity Read ↗

Causal link between childhood obesity and adult osteoporosis: An investigation through Mendelian randomization.Semantic proximity Read ↗

Causal relationship between Interleukin-27 expression levels and osteoporosis: a bidirectional mendelian randomization study.Semantic proximity Read ↗

Systematic evaluation for the causal effects of blood metabolites on osteoporosis: Genetic risk score and Mendelian randomization.Semantic proximity Read ↗

Causal effect between systemic inflammatory cytokines and osteoporotic pathological fractures: A bidirectional Mendelian randomization study.Semantic proximity Read ↗

Osteoporosis and sarcopenia-related traits: A bi-directional Mendelian randomization study.Semantic proximity Read ↗

Detecting causal relationship between metabolic traits and osteoporosis using multivariable Mendelian randomization.Semantic proximity Read ↗

Causal link between gut microbiota and osteoporosis analyzed via Mendelian randomization.Semantic proximity Read ↗

Dissecting Causal Relationships Between Plasma Metabolites and Osteoporosis: A Bidirectional Mendelian Randomization Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.