Article
Osteoporosis and sarcopenia-related traits: A bi-directional Mendelian randomization study.
Frontiers in endocrinology - 1 Jan 2022
Liu Chao, Liu Ningyuan, Xia Yu, Zhao Ziyue, Xiao Tao, Li Hui
Abstract excerpt
Background: With the advancement of world population aging, age-related osteoporosis (OP) and sarcopenia (SP) impose enormous clinical and economic burden on society. Evidence from accumulating studies indicates that they mutually influence one another. However, an observational study may be affected by potential confounders. Meanwhile, a Mendelian randomization (MR) study can overcome these confounders to assess...
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