Hyperlipidemia-associated gene variations and expression patterns revealed by whole-genome and transcriptome sequencing of rabbit models.

doi:10.1038/srep26942

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Article

Hyperlipidemia-associated gene variations and expression patterns revealed by whole-genome and transcriptome sequencing of rabbit models.

Scientific reports - 1 Jun 2016

Wang Zhen, Zhang Jifeng, Li Hong, Li Junyi, Niimi Manabu, Ding Guohui, Chen Haifeng, Xu Jie, Zhang Hongjiu, Xu Ze, Dai Yulin, Gui Tuantuan, Li Shengdi, Liu Zhi, Wu Sujuan, Cao Mushui, Zhou Lu, Lu Xingyu, Wang Junxia, Yang Jing, Fu Yunhe, Yang Dongshan, Song Jun, Zhu Tianqing, Li Shen, Ning Bo, Wang Ziyun, Koike Tomonari, Shiomi Masashi, Liu Enqi, Chen Luonan, Fan Jianglin, Chen Y Eugene, Li Yixue

Abstract excerpt

The rabbit (Oryctolagus cuniculus) is an important experimental animal for studying human diseases, such as hypercholesterolemia and atherosclerosis. Despite this, genetic information and RNA expression profiling of laboratory rabbits are lacking. Here, we characterized the whole-genome variants of three breeds of the most popular experimental rabbits, New Zealand White (NZW), Japanese White (JW) and Watanabe...

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PMID: 27245873
DOI: 10.1038/srep26942
PMCID: PMC4887883

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