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Quantitative Assessment of the Effects of IL-1ß -511 C>T Variant on Breast Cancer Risk: An Updated Meta-Analysis of 3331 Cases and 3609 Controls.

Laboratory medicine - 4 Jan 2021

Harati-Sadegh Mahdiyeh, Mohammadoo-Khorasani Milad, Sargazi Saman, Saravani Ramin, Shahraki Sheida, Eskandari Ebrahim

Abstract excerpt

OBJECTIVE: Growing evidence suggests that IL-1β -511C>T, as a functional variant, affects the risk of developing breast cancer (BC); however, the results have not been conclusive. This meta-analysis was conducted to estimate the link between this variant and BC risk. METHODS: We retrieved available publications on IL-1β -511C>T polymorphism by conducting a comprehensive literature search on the Web of Science,...

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PMID: 32754752
DOI: 10.1093/labmed/lmaa055

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