Article
Systematic review and meta-analysis on the association between IL-1B polymorphisms and cancer risk.
PloS one - 1 Jan 2013
Xu Jiali, Yin Zhiqiang, Cao Songyu, Gao Wen, Liu Lingxiang, Yin Yongmei, Liu Ping, Shu Yongqian
Abstract excerpt
BACKGROUND: Interleukin-1 beta (IL-1β), a pro-inflammatory cytokine, is emerging as a key mediator of carcinogenesis that characterizes host-environment interactions. Epidemiological studies investigating the association between two polymorphisms of IL-1B (-511C/T and +3954C/T) and cancer susceptibility have shown conflicting results. The aim of this study is to derive a more precise estimation of the...
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