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Article

Genetic determinants of UV-susceptibility in non-melanoma skin cancer.

PloS one - 1 Jan 2011

Welsh Marleen M, Karagas Margaret R, Kuriger Jacquelyn K, Houseman Andres, Spencer Steven K, Perry Ann E, Nelson Heather H

Abstract excerpt

A milieu of cytokines and signaling molecules are involved in the induction of UV-induced immune suppression and thus the etiology of non-melanoma skin cancer (NMSC). Targeting the UV-induced immunosuppression pathway, and using a large population based study of NMSC, we have investigated the risk associated with functional variants in 10 genes (IL10, IL4, IL4R, TNF, TNFR2, HTR2A, HRH2, IL12B, PTGS2, and HAL)....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21760883
DOI: 10.1371/journal.pone.0020019
PMCID: PMC3132750

Genes

HAL
HRH2
PTGS2
TNF

Provenance

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