Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CONNECT4 APOE: A randomized trial of telephone versus real-time two-way videoconference for disclosure of APOE genotype results in cognitively unimpaired adults.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Jul 2026

Wood Elisabeth McCarty, Langbaum Jessica B, Egleston Brian L, Ofidis Demetrios, Cacioppo Cara, Langlois Carolyn M, Weinberg Michelle, Kim Scott Y H, Reiman Eric M, Tariot Pierre N, Roberts J Scott, Karlawish Jason, Bradbury Angela R

Abstract excerpt

INTRODUCTION: Data are needed to inform best practices for disclosing apolipoprotein E (APOE) results given increasing indications for testing. METHODS: CONNECT4, a multi-center, randomized trial (NCT02978729) compared disclosure of APOE genotype by videoconference or telephone among cognitively unimpaired adults 60-75 years of age. Outcomes were collected at baseline, 2-7 days, 6 weeks, and 6 months. RESULTS: A...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Apolipoproteins E

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Depression

Share to APOE gene

Share to Genotype

Source

Open in PubMed Open full text

Identifiers

PMID: 42509665
DOI: 10.1002/alz.71658
PMCID: PMC13408020

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CONNECT4 APOE: A randomized trial of telephone versus real-time two-way videoconference for disclosure of APOE genotype results in cognitively unimpaired adults.PMID 42509665Read ↗

A randomized controlled trial of disclosing genetic risk information for Alzheimer disease via telephone.Semantic proximity Read ↗

Impact of learning APOE genotype on cognitively unimpaired adults: a pre-screening cohort study of the Alzheimer's Prevention Initiative Generation Study 1.Semantic proximity Read ↗

Disclosure of APOE genotype for risk of Alzheimer's disease.Semantic proximity Read ↗

Using Alzheimer's disease as a model for genetic risk disclosure: implications for personal genomics.Semantic proximity Read ↗

Effectiveness of a condensed protocol for disclosing APOE genotype and providing risk education for Alzheimer disease.Semantic proximity Read ↗

Disclosing genetic risk of Alzheimer's disease to cognitively impaired patients and visit companions: Findings from the REVEAL Study.Semantic proximity Read ↗

Disclosing Genetic Risk of Alzheimer's Disease to Cognitively Unimpaired Older Adults: Findings from the Study of Knowledge and Reactions to APOE Testing (SOKRATES II).Semantic proximity Read ↗

Disclosing Pleiotropic Effects During Genetic Risk Assessment for Alzheimer Disease: A Randomized Trial.Semantic proximity Read ↗

Interest in genetic susceptibility testing and disclosure of AD dementia risk in cognitively normal adults: A survey studySemantic proximity Read ↗

Participant attitudes toward returning individual results from CADASIL researchSemantic proximity Read ↗

A randomized noninferiority trial of condensed protocols for genetic risk disclosure of Alzheimer's disease.Semantic proximity Read ↗

The Effects of Subjective Cognitive Decline on APOE Genotype Disclosure in the Butler Hospital Alzheimer's Prevention Registry.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.