Article
Disclosing Genetic Risk of Alzheimer's Disease to Cognitively Unimpaired Older Adults: Findings from the Study of Knowledge and Reactions to APOE Testing (SOKRATES II).
Journal of Alzheimer's disease : JAD - 1 Jan 2021
Largent Emily A, Bhardwaj Twisha, Abera Maramawit, Stites Shana D, Harkins Kristin, Lerner Alan J, Bradbury Angela R, Karlawish Jason
Abstract excerpt
BACKGROUND: Current practice guidelines recommend against Apolipoprotein E (APOE) testing. However, advances in Alzheimer's disease (AD) research and care may soon change this. OBJECTIVE: To examine longitudinally the experience of learning an APOE result and, if an ɛ4 carrier, taking a disease-specific treatment to reduce one's risk of AD. METHODS: Fifty ɛ4 carriers and 20 non-carriers completed semi-structured...
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