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Article

Disclosure of APOE genotype for risk of Alzheimer's disease.

The New England journal of medicine - 16 Jul 2009

Green Robert C, Roberts J Scott, Cupples L Adrienne, Relkin Norman R, Whitehouse Peter J, Brown Tamsen, Eckert Susan LaRusse, Butson Melissa, Sadovnick A Dessa, Quaid Kimberly A, Chen Clara, Cook-Deegan Robert, Farrer Lindsay A

Abstract excerpt

BACKGROUND: The apolipoprotein E (APOE) genotype provides information on the risk of Alzheimer's disease, but the genotyping of patients and their family members has been discouraged. We examined the effect of genotype disclosure in a prospective, randomized, controlled trial. METHODS: We randomly assigned 162 asymptomatic adults who had a parent with Alzheimer's disease to receive the results of their own APOE...

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Source

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Identifiers

PMID: 19605829
DOI: 10.1056/NEJMoa0809578
PMCID: PMC2778270

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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