Article
Effectiveness of a condensed protocol for disclosing APOE genotype and providing risk education for Alzheimer disease.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Aug 2012
Roberts J Scott, Chen Clara A, Uhlmann Wendy R, Green Robert C
Abstract excerpt
PURPOSE: Brief, effective models of patient genetic education are needed for common, complex diseases. Using Alzheimer disease as a model, we compared participants' risk knowledge and recall in extended versus condensed education protocols. METHODS: A four-site randomized clinical trial enrolled 280 first-degree relatives of individuals with Alzheimer disease (mean age = 58 years, 71% female); each received...
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