Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A randomized noninferiority trial of condensed protocols for genetic risk disclosure of Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Oct 2015

Green Robert C, Christensen Kurt D, Cupples L Adrienne, Relkin Norman R, Whitehouse Peter J, Royal Charmaine D M, Obisesan Thomas O, Cook-Deegan Robert, Linnenbringer Erin, Butson Melissa Barber, Fasaye Grace-Ann, Levinson Elana, Roberts J Scott

Abstract excerpt

INTRODUCTION: Conventional multisession genetic counseling is currently recommended when disclosing apolipoprotein E (APOE) genotype for the risk of Alzheimer's disease (AD) in cognitively normal individuals. The objective of this study was to evaluate the safety of brief disclosure protocols for disclosing APOE genotype for the risk of AD. METHODS: A randomized, multicenter noninferiority trial was conducted at...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Anxiety

Share to Apolipoproteins E

Share to Black or African American

Share to Disclosure

Share to Genetic Counseling

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 25499536
DOI: 10.1016/j.jalz.2014.10.014
PMCID: PMC4461546

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A randomized noninferiority trial of condensed protocols for genetic risk disclosure of Alzheimer's disease.PMID 25499536Read ↗

Effectiveness of a condensed protocol for disclosing APOE genotype and providing risk education for Alzheimer disease.Semantic proximity Read ↗

A randomized controlled trial of disclosing genetic risk information for Alzheimer disease via telephone.Semantic proximity Read ↗

Disclosure of APOE genotype for risk of Alzheimer's disease.Semantic proximity Read ↗

Disclosing Pleiotropic Effects During Genetic Risk Assessment for Alzheimer Disease: A Randomized Trial.Semantic proximity Read ↗

Using Alzheimer's disease as a model for genetic risk disclosure: implications for personal genomics.Semantic proximity Read ↗

Safety and Tolerability of APOE Genotyping and Disclosure in Cognitively Normal Volunteers From the Butler Alzheimer's Prevention Registry.Semantic proximity Read ↗

Health behavior changes after genetic risk assessment for Alzheimer disease: The REVEAL Study.Semantic proximity Read ↗

Genetic risk assessment for adult children of people with Alzheimer's disease: the Risk Evaluation and Education for Alzheimer's Disease (REVEAL) study.Semantic proximity Read ↗

Estimating risk curves for first-degree relatives of patients with Alzheimer's disease: the REVEAL study.Semantic proximity Read ↗

The Effects of Subjective Cognitive Decline on APOE Genotype Disclosure in the Butler Hospital Alzheimer's Prevention Registry.Semantic proximity Read ↗

Comparing test-specific distress of susceptibility versus deterministic genetic testing for Alzheimer's disease.Semantic proximity Read ↗

Recall of disclosed apolipoprotein E genotype and lifetime risk estimate for Alzheimer's disease: the REVEAL Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.