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Article

Plasma lipidome and intracranial aneurysms: A univariable and multivariable Mendelian randomization study.

Neuroscience - 7 May 2025

Liu Xinke, Wei Dachao, Lin Jun, Dong Linggen, Li Youxiang, Lv Ming

Abstract excerpt

BACKGROUND: Recent studies suggest that plasma lipids, including lipoproteins and fatty acids, may contribute to the pathogenesis of intracranial aneurysms (IAs). However, the relationship between a broader range of plasma lipids and IA risk remains unclear. This study uses the Mendelian randomization (MR) approach to explore the causal relationships between 179 plasma lipids and the risk of IAs. METHODS: We used...

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Identifiers

PMID: 40068718
DOI: 10.1016/j.neuroscience.2025.03.018

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