Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

LncRNA RP11-708J19.2 promotes colorectal cancer progression by binding to SIRT7 via regulating H3K18ac.

European journal of histochemistry : EJH - 23 Jul 2026

Ma Jiali, Tian Xianglong, Qiu Yiwen, Zhao Chen, Wang Jinghui, Jia Rongrong

Abstract excerpt

Colorectal cancer (CRC) is a prevalent malignancy with a complex genetic basis. Recent genome-wide association studies (GWAS) have identified a susceptibility locus at 3p21.31, however, the functional SNP(s) underlying the association between the 3p21.31 region and CRC remain to be elucidated. In this study, we identified rs2101247 as the potential functional SNP and further demonstrated that rs2101247 is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Acetylation

Share to Apoptosis

Share to Colorectal Neoplasms

Share to Disease Progression

Share to Gene Expression Regulation, Neoplastic

Share to Histones

Share to RNA, Long Noncoding

Share to Sirtuins

Source

Open in PubMed Open full text

Identifiers

PMID: 42489630
DOI: 10.4081/ejh.2026.4560
PMCID: PMC13530957

Genes

SIRT7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

LncRNA RP11-708J19.2 promotes colorectal cancer progression by binding to SIRT7 via regulating H3K18ac.PMID 42489630Read ↗

Integrated systematic functional screen and fine-mapping decipher the role and genetic regulation of RPS19 in colorectal cancer development.Semantic proximity Read ↗

Association between genetic variants in the promoter region of a novel antisense long noncoding RNA RP11-392P7.6 and colorectal cancer risk.Semantic proximity Read ↗

Three functional variants were identified to affect RPS24 expression and significantly associated with risk of colorectal cancer.Semantic proximity Read ↗

Polymorphisms of a novel long non-coding RNA RP11-108K3.2 with colorectal cancer susceptibility and their effects on its expression.Semantic proximity Read ↗

LINC02257 regulates malignant phenotypes of colorectal cancer via interacting with miR-1273g-3p and YB1.Semantic proximity Read ↗

Association of a novel genetic variant in RP11-650L12.2 with risk of colorectal cancer in Han Chinese population.Semantic proximity Read ↗

Rs12039395 Variant Influences the Expression of hsa-miR-181a-5p and PTEN Toward Colorectal Cancer Risk.Semantic proximity Read ↗

Analyzing large-scale samples highlights significant association between rs10411210 polymorphism and colorectal cancer.Semantic proximity Read ↗

Identification of potential functional variants and genes at 18q21.1 associated with the carcinogenesis of colorectal cancer.Semantic proximity Read ↗

Biological functions and clinical significance of the newly identified long non‑coding RNA RP1‑85F18.6 in colorectal cancerSemantic proximity Read ↗

A novel SNP in promoter region of RP11-3N2.1 is associated with reduced risk of colorectal cancer.Semantic proximity Read ↗

Long noncoding RNA RP11-757G1.5 sponges miR-139-5p and upregulates YAP1 thereby promoting the proliferation and liver, spleen metastasis of colorectal cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.