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Article

LINC02257 regulates malignant phenotypes of colorectal cancer via interacting with miR-1273g-3p and YB1.

Cell death & disease - 18 Dec 2024

Park Mi-So, Jeong Seong Dong, Shin Chang Hoon, Cha Soojin, Yu Ahran, Kim Eun Ju, Gorospe Myriam, Cho Yong Beom, Won Hong-Hee, Kim Hyeon Ho

Abstract excerpt

Colorectal cancer (CRC) is the third most common cancer diagnosed and the second leading cause of cancer-related deaths. Emerging evidence has indicated that long non-coding RNAs (lncRNAs) are involved in the progression of various types of cancer. In this study, we aimed to identify potential causal lncRNAs in CRC through comprehensive multilevel bioinformatics analyses, coupled with functional validation. Our...

Topics

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Cell Movement
Colorectal Neoplasms
Epithelial-Mesenchymal Transition
Mice, Nude
MicroRNAs

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Plasminogen Activator Inhibitor 1

RNA, Long Noncoding

Y-Box-Binding Protein 1

Source

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Identifiers

PMID: 39695079
DOI: 10.1038/s41419-024-07259-4
PMCID: PMC11655847

Genes

SERPINE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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LINC02257 regulates malignant phenotypes of colorectal cancer via interacting with miR-1273g-3p and YB1.PMID 39695079Read ↗

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LINC02595 promotes tumor progression in colorectal cancer by inhibiting miR‐203b‐3p activity and facilitating BCL2L1 expressionSemantic proximity Read ↗

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Long noncoding RNA RP11-757G1.5 sponges miR-139-5p and upregulates YAP1 thereby promoting the proliferation and liver, spleen metastasis of colorectal cancerSemantic proximity Read ↗

Long noncoding RNA RP11-757G1.5 sponges miR-139-5p and upregulates YAP1 thereby promoting the proliferation and liver, spleen metastasis of colorectal cancerSemantic proximity Read ↗

LINC02257, an Enhancer RNA of Prognostic Value in Colon Adenocarcinoma, Correlates With Multi-Omics Immunotherapy-Related Analysis in 33 CancersSemantic proximity Read ↗

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