Article
Analyzing large-scale samples highlights significant association between rs10411210 polymorphism and colorectal cancer.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Aug 2015
He Dongfeng, Ma Lihong, Feng Rennan, Zhang Liangcai, Jiang Yongshuai, Zhang Yanqiao, Liu Guiyou
Abstract excerpt
Colorectal cancer (CRC) is the third most common form of cancer and the second leading cause of cancer-related death in the Western countries. In order to detect common CRC genetic variants, genome-wide association studies (GWAS) have been performed and reported some novel CRC susceptibility variants. RHPN2 is located on 9q13.11, which encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase...
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