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Article

Association of p-glycoprotein and bile salt export pump gene polymorphisms with advanced liver disease in hepatitis C virus infected patients.

Memorias do Instituto Oswaldo Cruz - 1 Jan 2026

Campos Letícia Bomfim, Almeida Nathália Alves Araújo de, Pires Marcia Maria Amendola, Brandão-Mello Carlos Eduardo, Villar Livia Melo, Barros José Júnior França de, Paula Vanessa Salete de

Abstract excerpt

BACKGROUND: Single-nucleotide polymorphisms (SNPs) can influence the hepatitis C virus (HCV) infection and progression. ABCB1-gene SNPs - c.1236C>T, c.2677G>T and c.3435C>T - are associated with drug efficacy, hepatotoxicity, and liver injury. ABCB11 c.1331T>C is associated with cholestasis and altered bilirubin levels, potentially worsening liver disease. OBJECTIVE: To investigate the impact of ABCB1 and ABCB11...

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Share to ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42484281
DOI: 10.1590/0074-02760250173
PMCID: PMC13387806

Genes

ABCB1
ABCB11

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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