Article
APOB codon 4311 polymorphism is associated with hepatitis C virus infection through altered lipid metabolism.
BMC gastroenterology - 30 Jan 2018
Harada Rie, Kimura Masako, Sato Yasushi, Taniguchi Tatsuya, Tomonari Tetsu, Tanaka Takahiro, Tanaka Hironori, Muguruma Naoki, Shinomiya Hirohiko, Honda Hirohito, Imoto Issei, Sogabe Masahiro, Okahisa Toshiya, Takayama Tetsuji
Abstract excerpt
BACKGROUND: It has been reported that some single-nucleotide polymorphisms (SNPs) in lipid regulators such as apolipoproteins and cell surface molecules for hepatitis C virus (HCV) entry into hepatocytes are associated with HCV infection. However, it is unknown how HCV infection is affected by altered lipid metabolism resulting from the SNPs. We investigated the relationship between these SNPs and HCV infection...
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