Diagnosis of cirrhosis in patients with chronic hepatitis C genotype 4: Role of ABCB11 genotype polymorphism and plasma bile acid levels.

doi:10.5152/tjg.2018.17570

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Article

Diagnosis of cirrhosis in patients with chronic hepatitis C genotype 4: Role of ABCB11 genotype polymorphism and plasma bile acid levels.

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology - 1 May 2018

Besheer Tarek, Arafa Mona, El-Maksoud Mohamed Abd, Elalfy Hatem, Hasson Amany, Zalata Khaled, Elkashef Wagdi, Elshahawy Heba, Raafat Doaa, Elemshaty Wafaa, Elsayed Eman, Zaghloul Hosam, Razek Ahmed Abdel, El-Bendary Mahmoud

Abstract excerpt

BACKGROUND/AIMS: Chronic hepatitis C (CHC)-related mortality generally results from cirrhosis and subsequent complications. We aimed to investigate the potential role of plasma bile acid levels and ABCB11 1331T > C (V444A, rs2287622) (ATP-binding cassette subfamily B, member 11) gene polymorphism in fibrosis prediction in CHC genotype 4 patients. MATERIALS AND METHODS: This case control study included 85 healthy...

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Identifiers

PMID: 29755014
DOI: 10.5152/tjg.2018.17570
PMCID: PMC6284664

Genes

ABCB11

Variants

rs2287622

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