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Differential associations of oral health with early- and late-onset dementia: a prospective analysis of the UK Biobank.

The journals of gerontology. Series A, Biological sciences and medical sciences - 4 Aug 2026

Liu Yunrui, Qi Xiang, Luo Huabin, Liu Ruotong, Xu Zhijing, Wu Bei

Abstract excerpt

BACKGROUND: Poor oral health is a modifiable risk factor for dementia, but whether the associations differ by age at onset and are modified by genetic susceptibility remains unclear. METHODS: In this prospective cohort study of 364,231 dementia-free UK Biobank participants, we examined associations between oral health indicators and incident early- and late-onset dementia (EOD and LOD). Genetic susceptibility was...

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PMID: 42434961
DOI: 10.1093/gerona/glag179

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APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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