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Occlusion dysfunction and Alzheimer’s disease: Mendelian randomization study

5 Jul 2024

Abstract excerpt

Aim: Occlusion dysfunction (OD) is increasingly linked to Alzheimer's disease (AD). This study aimed to elucidate the causal relationship between OD and AD using Mendelian randomization (MR) analysis. Materials and methods: Genome-wide association study (GWAS) meta-analysis data obtained from FinnGen, IEU Open GWAS, and UK Biobank (UKBB) was represented as instrumental variables. We validated the causal...

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PMID: 39035234
DOI: 10.3389/fnagi.2024.1423322

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