Article
Donor selection in living-donor lung transplantation for familial pulmonary fibrosis: A narrative review and single-center practical approach.
Respiratory investigation - 1 Sept 2026
Handa Tomohiro, Chen-Yoshikawa Toyofumi Fengshi, Kawasaki Hidenori, Ikezoe Kohei, Nakatsuka Yoshinari, Kimura Jumpei, Mineura Katsutaka, Sakanoue Ichiro, Kayawake Hidenao, Tanaka Satona, Nakajima Daisuke, Tanizawa Kiminobu, Hirai Toyohiro
Abstract excerpt
In Japan, living-donor lobar lung transplantation (LDLLT) remains an important therapeutic option because of the persistent shortage of brain-dead donors. Interstitial lung diseases (ILDs) are a major indication for transplantation; however, the use of biologically related donors raises concerns regarding shared genetic susceptibility. Approximately 20% of ILD patients have a family history of ILD, referred to as...
Read the complete abstract on PubMedTopics
- Humans
- Lung Transplantation
- Living Donors
- Genetic Predisposition to Disease
- Donor Selection