Article
Increased frequency of the angiotensin-converting enzyme gene D-allele is associated with noninfectious pulmonary dysfunction following allogeneic stem cell transplant.
Bone marrow transplantation - 1 Oct 2005
Onizuka M, Kasai M, Oba T, Atsuta Y, Terakura S, Suzuki R, Kitaori K, Miyamura K, Hotta T, Kodera Y
Abstract excerpt
Noninfectious pulmonary dysfunction (NIPD) is a common and often fatal complication associated with allogeneic hematopoietic stem cell transplantation (HSCT). An insertion/deletion polymorphism in the angiotensin-converting enzyme (ACE) gene has been extensively studied in relation to cardiovascular and renal disease, and lung fibrosis. In pulmonary fibrosis, D-allele frequency is significantly higher than in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.